Lichen simplex chronicus (LSC) (also known as neurodermatitis) is a skin disorder characterized by chronic itching and scratching. The constant scratching causes thick, leathery, darkened, (lichenified) skin. This condition is associated with many factors, including the scratch-itch cycle, psychological stressors, and atopy. LSC is more common between ages 35 and 50 and is seen approximately twice as often in women compared to men.
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Lichen Simplex Chronicus (LSC) 是一种皮肤疾病,表现为局部皮肤增厚并伴有强烈瘙痒,常在表面出现划痕。受累部位的颜色可从粉红色到深棕色不等,随病程进展,中心可能变浅而边缘颜色加深。与另一种表现为全身多发结节的瘙痒性疾病 prurigo nodularis (PN) 不同,LSC 通常局限于特定部位或少数区域。LSC 有时也被称为神经性皮炎,属于长期持续的瘙痒性皮肤病之一。 LSC is a localized skin disorder clinically characterized by lichenified plaques of skin often accompanied by overlying excoriations. These plaques can become discoloured, with varying shades of erythema ranging from pink to dark brown. Over a longer course, it may transform into a hypopigmented plaque with a darker border. They are localized to specific areas of the body as one or a few plaques. This is in contrast to prurigo nodularis (PN), another chronic pruritic condition, which is frequently more broadly distributed across multiple regions of the body as nodules. While LSC may sometimes be referred to as a neurodermatitis, which encompasses other chronic itchy conditions.
Lichen simplex chronicus 是一种慢性神经性皮炎,皮肤出现干燥、斑块并增厚。其发生原因是经常刮擦或摩擦局部皮肤,导致表皮增厚。 Lichen simplex chronicus is defined as a common form of chronic neurodermatitis that presents as dry, patchy areas of skin that are scaly and thick. The hypertrophic epidermis generally seen is typically the result of habitual scratching or rubbing of a specific area of the skin.
这是一种慢性、逐渐进展的皮肤疾病。对患者而言,抓挠已成为一种习惯。患有慢性单纯性苔藓 (lichen simplex chronicus) 的人常感强烈瘙痒,往往难以控制地反复抓挠同一部位。
○ 治疗 - 非处方药
用肥皂清洗病变部位并无帮助,反而可能使情况恶化。
非处方强度的类固醇软膏疗效有限,通常需连续使用一周或更长时间才能见效。
#Hydrocortisone ointment
非处方抗组胺药。西替利嗪或左西替利嗪的止痒效果优于非索非那定,但可能导致嗜睡。
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]